Rosenstein Laboratory for Embedded Bioelectronics

Publications

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Click Here for a combined BibTex file for the publications below.

X. Lian, E. Stang, K. Hu, P. R. Guduru, and J. K. Rosenstein, A 5,000,000 frame/sec Burst-Mode Cryogenic Thermal Imager with On-Chip Frame Memory. IEEE Solid-State Circuits Letters (SSC-L), 2024.
 
M. Abdelatty, J. Incandela, K. Hu, J. W. Larkin, S. Reda, and J. K. Rosenstein, Electrical Capacitance Tomography of Cell Cultures on a CMOS Microelectrode Array. IEEE Transactions on Biomedical Circuits and Systems, 2024.
 
A. Agiza, S. Marriott, J. K. Rosenstein, E. Kim, and S. Reda, pH-Controlled Enzymatic Computing for Digital Circuits and Neural Networks.” Physical Chemistry Chemical Physics, 2024.
 
S. Gumus, , D. Biechele-Speziale, K.E. Manz, K.D. Pennell, B.M. Rubenstein, and J. K. Rosenstein, Repurposing Waste Chemicals for Sustainable and Durable Molecular Data Storage, ACS Omega 2024.
 
M. Abdelatty, J. Incandela, K. Hu, J. W. Larkin, S. Reda, and J. K. Rosenstein, Microscale 3-D Capacitance Tomography with a CMOS Sensor Array, IEEE Biomedical Circuits and Systems Conference (BioCAS), 2023.
arXiv preprint
P. Joshi, K. Hu, J. W. Larkin, and J. K. Rosenstein, Programmable Electrochemical Stimulation on a Large-Scale CMOS Microelectrode Array, IEEE Biomedical Circuits and Systems Conference (BioCAS), 2022.
 
K. Hu, J. Ho, and J. K. Rosenstein, Super-Resolution Electrochemical Impedance Imaging with a 512x256 CMOS Sensor Array, IEEE Transactions on Biomedical Circuits and Systems, 2022.
 
K. Hu, J. Incandela, X. Lian,, J. W. Larkin, and J. K. Rosenstein, A 13.1 mm2 512 x 256 Multimodal CMOS Array for Spatiochemical Imaging of Bacterial Biofilms IEEE Custom Integrated Circuits Conference (CICC), 2022.
  
K. Hu, C. Arcadia, and J. K. Rosenstein, Super-Resolution Electrochemical Impedance Imaging with a 100x100 CMOS Sensor Array, IEEE Biomedical Circuits and Systems Conference (BioCAS), 2021.
  • Winner, Best Paper Award
bioRxiv preprint
K. Hu, C. Arcadia, and J. K. Rosenstein, A Fringe Field Shaping CMOS Capacitive Imaging Array, IEEE Sensors Conference, 2021.
 
E. Kennedy, J. Geiser, C. E. Arcadia, P. M. Weber, C. Rose, B.M. Rubenstein, and J. K. Rosenstein, Secret Messaging with Endogenous Chemistry, Scientific Reports, 2021.
 pdf
S. Dai, C. Tulloss, X. Lian, K. Hu, S. Reda, and J. K. Rosenstein, "Low Power Current-Mode Relaxation Oscillators for Temperature and Supply Voltage Monitoring", Book Chapter in VLSI-SoC: Design Trends, IFIP Advances in Information and Communication Technology series, vol. 621, 2021.
  
C. Arcadia, K. Hu, S. Epstein, M. Wanunu, A. Adler, and J. K. Rosenstein, CMOS Electrochemical Imaging Arrays for the Detection and Classification of Microorganisms, IEEE International Symposium on Circuits and Systems (ISCAS), 2021.
 bioRxiv preprint
C. Arcadia, A. Dombroski, K. Oakley, S. L. Chen, H. Tann, C. Rose, E. Kim, B. M. Rubenstein, S. Reda, and J. K. Rosenstein, Leveraging Autocatalytic Reactions for Digital Image Classification, Chemical Science, 2021.
pdf
K. Hu, C. Arcadia, and J. K. Rosenstein, A Large-Scale Multi-Modal CMOS Biosensor Array with 131,072 Pixels and Code Division Multiplexed Readout, IEEE Solid-State Circuits Letters (SSC-L), 2021.
 
A. Dombroski, K. Oakley, , F. Nouraei, S.L. Chen, C. Rose, B. Rubenstein, J. Rosenstein, S. Reda and E. Kim, Implementing parallel arithmetic via acetylation and its application to chemical image processing, Proceedings of the Royal Society A, 2021.
 
C. Arcadia, E. Kennedy, J. Geiser, A. Dombroski, K. Oakley, S.L. Chen, L. Sprague, M. Ozmen, J. Sello, P.M. Weber, S. Reda, C. Rose, E. Kim, B. M. Rubenstein, and J. K. Rosenstein, Multicomponent Molecular Memory, Nature Communications, 2020.
pdf
P. Shakya, E. Kennedy, C. Rose, and J. K. Rosenstein, High-Dimensional Time Series Feature Extraction for Low-Cost Machine Olfaction, IEEE Sensors Journal, 2020.
pdf
S. Dai, K. Hu, and J. K. Rosenstein, "A Segmented SAR/SS ADC with Digital Error Correction and Programmable Resolution for Column-Parallel Sensor Arrays," IEEE International Symposium on Circuits and Systems (ISCAS), 2020.
pdf
S. Dai, C. Tulloss, X. Lian, K. Hu, S. Reda, and J. K. Rosenstein, Temperature and Supply Voltage Monitoring with Current-mode Relaxation Oscillators, IEEE International Conference on Very Large Scale Integration (VLSI-SoC), 2020.
  • Finalist for Best Paper Award
 
X. Lian, S. Reda, and J. K. Rosenstein, Simultaneous Estimation of Temperature and Voltage from Digital Delay Diversity, IEEE International Conference on Very Large Scale Integration (VLSI-SoC), 2020.
 
J. K. Rosenstein, C. Rose, S. Reda, P. M. Weber, E. Kim, J. Sello, J. Geiser, E. Kennedy, C. Arcadia, A. Dombroski, K. Oakley, S. L. Chen, H. Tann, B. M. Rubenstein, Principles of Information Storage in Small-Molecule Mixtures, IEEE Transactions on NanoBioscience, 2020.
pdf /
preprint
K. Hu, E. Kennedy, and J. K. Rosenstein, High Frequency Dielectric Spectroscopy Array with Code Division Multiplexing for Biological Imaging, IEEE Biomedical Circuits and Systems Conference (BioCAS), 2019.
pdf
K. Hu, X. Lian, S. Dai, and J. K. Rosenstein, Low Noise CMOS ISFETs Using In-Pixel Chopping, IEEE Biomedical Circuits and Systems Conference (BioCAS), 2019.
pdf
P. Shakya, E. Kennedy, C. Rose, and J. K. Rosenstein, Time Series Feature Extraction for Machine Olfaction, IEEE SENSORS Conference, 2019.
  • Finalist for Best Student Paper Award
pdf
E. Kennedy, C. Arcadia, J. Geiser, P. M. Weber, C. Rose, B. M. Rubenstein, and J. K. Rosenstein, Encoding Information in Synthetic Metabolomes, PLOS ONE, 2019.
 pdf
M. Ozmen, E. Kennedy, J. Rose, P. Shakya, J. K. Rosenstein, and C. Rose, High Speed Chemical Vapor Communication Using Photoionization Detectors in Turbulent Flow, IEEE Transactions on Molecular, Biological, and Multi-Scale Communications, 2019.
pdf
B. Foulon, Y. Liu, J. K. Rosenstein and B. M. Rubenstein, A Language for Molecular Computation, Chem, 5(12), pp.3017-3019, 2019.
 
J. Webster, P. Shakya, E. Kennedy, M. Caplan, C. Rose, and J. K. Rosenstein, TruffleBot: Low-Cost Multi-Parametric Machine Olfaction, IEEE Biomedical Circuits and Systems Conference (BioCAS), 2018.
 pdf / preprint
C. Arcadia, H. Tann, A. Dombroski, K. Ferguson, S. Chen, E. Kim, C. Rose, B. Rubenstein, S. Reda, and J. K. Rosenstein, Parallelized Linear Classification with Volumetric Chemical Perceptrons, IEEE Conference on Rebooting Computing (ICRC), 2018.
pdf / preprint
M. Carminati, J. K. Rosenstein, R. Thewes and H.-J. Yoo,, "Guest Editorial: Special Issue on Advances and Open Challenges for Integrated Circuits Detecting Bio Molecules," IEEE Transactions on Biomedical Circuits and Systems, vol. 12, no. 6, pp. 1334-1336, Dec. 2018.
  
M. Ozmen, E. Kennedy, J. Rose, P. Shakya, J. K. Rosenstein, and C. Rose, High Speed Chemical Vapor Communication Using Photoionization Detectors, IEEE Global Communications Conference (GLOBECOM), 2018.
pdf
R. Perera, C. Arcadia, J. K. Rosenstein, Probing the nucleation, growth, and evolution of hydrogen nanobubbles at single catalytic sites, Electrochimica Acta, 2018.
pdf
E. Kennedy, P. Shakya, M. Ozmen, C. Rose, J. K. Rosenstein, Spatiotemporal information preservation in turbulent vapor plumes, Applied Physics Letters, 2018.
pdf
D. A. Fleischer, S. Shekar, S. Dai, R. M. Field, J. Lary, J. K. Rosenstein, K. L. Shepard, CMOS-Integrated Low-Noise Junction Field-Effect Transistors for Bioelectronic Applications, IEEE Electron Devices Letters, 2018.
  
P. Shakya, E. Kennedy, C. Rose, J. K. Rosenstein, Correlated Transmission and Detection of Concentration-Modulated Chemical Vapor Plumes, IEEE Sensors Journal, 2018.
  
C. Rose, S. Reda, B. Rubenstein, J. K. Rosenstein, Computing With Chemicals: Perceptrons Using Mixtures of Small Molecules, IEEE International Symposium on Information Theory, 2018.
  
R. Perera, J. K. Rosenstein, Quasi-reference electrodes in confined electrochemical cells can result in in-situ production of metallic nanoparticles, Scientific Reports, 2018.
  
C. Arcadia, C. Reyes, J. K. Rosenstein, In-Situ Nanopore Fabrication and Single-Molecule Sensing with Microscale Liquid Contacts, ACS Nano, 2017.
  
J. Jimenez, S. Dai, J. K. Rosenstein, A Microwatt Front End and Asynchronous ADC for Sparse Biopotential Acquisition, Proceedings of the 60th Annual IEEE MWSCAS Conference, 2017.
  
S. Dai, J. K. Rosenstein, A 15-V bidirectional current clamp circuit for integrated patch clamp electrophysiology, IEEE Transactions on Circuits and Systems II, 2017.
  
S. Dai, R. T. Perera, Z. Yang, J. K. Rosenstein, A 155-dB Dynamic Range Current Measurement Front End for Electrochemical Biosensing, IEEE Transactions on Biomedical Circuits and Systems, 2016.
  
S. Shekar, D. J. Niedzwiecki, C. C. Chien, P. Ong, D. A. Fleischer, J. Lin, J. K. Rosenstein, M. Drndić, K. L. Shepard, Measurement of DNA Translocation Dynamics in a Solid-State Nanopore at 100 ns Temporal Resolution, Nano Letters, 2016.
  
S. Dai and J. K. Rosenstein A 14.4nW 122KHz dual-phase current-mode relaxation oscillator for near-zero-power sensors, Proceedings of the IEEE Custom Integrated Circuits Conference (CICC), 2015.
  
J. M. Roseman, J. Lin, S. Ramakrishnan, J. K. Rosenstein, and K. L. Shepard, Hybrid integrated biological–solid-state system powered with adenosine triphosphate, Nature Communications, 2015.
  
S. Dai and J. K. Rosenstein A Dual-Mode Low-Noise Nanosensor Front-End with 155-dB Dynamic Range, Proceedings of the IEEE Biomedical Circuits and Systems Conference (BioCAS), 2015.
  
Emmett, K. J., Rosenstein, J.K., Meent, J.-W. V. de, Shepard, K. L. & Wiggins, C. H. Statistical Inference for Nanopore Sequencing with a Biased Random Walk Model, Biophysical Journal, 2015.
  
Rosenstein, J.K., Lemay, S.G., Shepard, K.L. Single-Molecule Bioelectronics, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2015.
  
Bellin, D., Warren, S., Rosenstein, J.K., Shepard, K.L. Interfacing CMOS Electronics to Biological Systems, Biomedical Circuits and Systems Conference (BioCAS), 2014.
  
Weinreich, S., Rosenstein, J.K. A Wireless Glucose Sensor on a Paper Substrate, IEEE Engineering in Medicine and Biology Conference (EMBC), 2014. (undergraduate first author)
  
Bellin, D.L., Hassan, S., Rosenstein, J.K., Levine, P.M., Thimot, J., Emmett, K., Dietrich, L.E., Shepard, K.L. Integrated circuit-based electrochemical sensor for spatially resolved detection of redox-active metabolites in biofilms, Nature Communications, 2014.
  
Larkin, J., Henley, R., Muthukumar, M., Rosenstein, J.K., Wanunu, M. High-Bandwidth Protein Analysis Using Solid-State Nanopores, Biophysical Journal, 2014.
  
Larkin, J., Henley, R., Bell, D., Cohen-Karni, T., Rosenstein, J.K., Wanunu, M. Slow DNA Transport through Nanopores in Hafnium Oxide Membranes, ACS Nano, 2013.
  
Rosenstein, J., Shepard, K.L., Temporal Resolution of Nanopore Sensor Recordings. IEEE Engineering in Medicine and Biology Conference (IEEE-EMBC), 2013.
  
Rosenstein, J.K., Ramakrishnan, S., Roseman, J., Shepard, K.L. Single Ion Channel Recordings with CMOS-Anchored Lipid Membranes, Nano Letters, 2013.
  
Venta, K., Shemer, G., Puster, M., Rodriguez-Manzo, J.A., Balan, A., Rosenstein, J.K., Shepard, K.L., Drndić, M., Differentiation of short single-stranded DNA homopolymers in solid-state nanopores, ACS Nano, 2013.
  
Rosenstein, J.K., Wanunu, M., Merchant, C., Drndic, M., Shepard, K.L. Integrated Nanopore Sensing Platform with Sub-Microsecond Temporal Resolution, Nature Methods, 2012.  
Rosenstein, J., Shepard, K.L., High-Throughput Biology in the Time Domain: Improving Temporal Resolution of Single-Molecule Sensors, International Symposium on Circuits and Systems (ISCAS), 2012. (invited)
  
Rosenstein, J., Sorgenfrei, S., Shepard, K. L. Noise and bandwidth performance of single-molecule biosensors, Custom Integrated Circuits Conference (CICC), 2011.
  
Rosenstein, J., Ray, V., Drndic, M., Shepard, K.L. Nanopore DNA sensors in CMOS with on-chip low-noise preamplifiers, Solid-State Sensors, Actuators and Microsystems Conference (Transducers), 2011.
  
Rosenstein, J., Ray, V., Drndic, M., Shepard, K.L. Solid-state nanopores integrated with low-noise preamplifiers for high-bandwidth DNA analysis, IEEE/NIH Life Science Systems and Applications Workshop (LiSSA), 2011.